International Lyme And Associated Diseases Society
Leaders in Lyme Disease Education and Training

Boston, Massachusetts

November 2-4, 2012

Antimicrobial resistance of Borrelia bugdorferi biofilm
Eva Sapi, PhD

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Eva Sapi, PhD received her Ph.D. degree in Genetics from the University of Eotvos Lorand (Budapest Hungary). She is an Associate Professor at the University of New Haven where she teaches graduate biology courses and carries out Lyme disease research with her graduate students. To date, over 80 graduate students have received training in Lyme disease related research.
In the last several years UNH Lyme disease research group has identified an alarming increase in the co-infection rate in deer ticks, including discovery of novel co-infections such microfilarial nematode species.
Her recent studies investigate the different forms of Borrelia burgdorferi to better understand how Borrelia can hide from the immune system as well as from antimicrobial therapies. Her recent research shows that Borrelia burgdorferi is capable forming a protective layer around itself ??" called biofilm ??" which could render it to be very resistant to antibiotics and provide a logical explanation as to why extensive antibiotic treatment for patients with a tick-bite history could fail. The goal of her research group is to identify novel antibacterial agents that are effective in killing all forms of Borrelia burgdorferi.
Dr. Sapi organized and chaired four Lyme Disease Symposiums at the University of New Haven during the last several years.