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Phylogenetic tree depicting relationships among various Borrelia species. Branches are divided into groups: Lyme disease in one cluster and Relapsing Fever in another. Bootstrap values are indicated on multiple nodes. E. coli Lambda phage is shown as an outgroup.

The successful treatment of Lyme disease (LD) is contingent on accurate diagnosis. However, current laboratory detection assays lack sensitivity in the early stages of the disease. Because delayed diagnosis of LD incurs high healthcare costs and great suffering, new highly sensitive tests are in need. To overcome these challenges, we developed an internally controlled quantitative…

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A forthcoming special issue of  Tropical Medicine & Infectious Diseases will be co-edited by ILADS member Dr. Kenneth B. Liegner.  The special issue will be titled “Tick-Borne Diseases and the Spirochetoses in the Tropical Zone“.  Manuscript submission information for the special issue can be found here. The deadline for manuscript submissions is 25 October 2021.…

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ILADS member Richard Horowitz published a new article titled Efficacy of Double-Dose Dapsone Combination Therapy in the Treatment of Chronic Lyme Disease/Post-Treatment Lyme Disease Syndrome (PTLDS) and Associated Co-infections: A Report of Three Cases and Retrospective Chart Review in the journal Antibiotics. ABSTRACT: Three patients with multi-year histories of relapsing and remitting Lyme disease and associated…

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From the blog of ILADS member Daniel Cameron, MD, MPH: Babesia, a parasitic infection usually transmitted through a tick bite, was once thought to be a coastal tick-borne disease limited to Suffolk County on Long Island. Some doctors had been reluctant to acknowledge that Babesia could be found in other locations. But in 2001, Babesia…

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ILADS member John D. Scott published a new paper titled Monitoring of Nesting Songbirds Detects Established Population of Blacklegged Ticks and Associated Lyme Disease Endemic Area in Canada in the journal Healthcare. ABSTRACT: This study provides a novel method of documenting established populations of bird-feeding ticks. Single populations of the blacklegged tick, Ixodes scapularis, and the…

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ILADS member Robert C. Bransfield, MD published a new paper titled A Clinical Diagnostic System for Late-Stage Neuropsychiatric Lyme Borreliosis Based upon an Analysis of 100 Patients in the journal Healthcare.  ABSTRACT: Many late-stage chronic Lyme disease clinical findings are neuropsychiatric. A total clinical assessment is critical in diagnosis, especially since controversy surrounds the reliability…

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The NIH is developing a strategic plan to advance tickborne disease (TBD) research and development over the next five years and beyond.  This Request for Information (RFI) invited comments and suggestions on the tickborne diseases (TBD) research priorities NIH should continue or adopt over the coming years. The deadline for submission was March 13, 2019. …

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